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1

Modulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C Virus

Dorobantu, Cristina M., Albulescu, Lucian, Harak, Christian, Feng, Qian, van Kampen, Mirjam, Strating, Jeroen R. P. M., Gorbalenya, Alexander E., Lohmann, Volker, van der Schaar, Hilde M., van Kuppeve

Journal:

Year:

2015

Language:

english

File:

PDF, 10.47 MB

english, 2015

2

Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication

van der Schaar, Hilde M, van der Linden, Lonneke, Lanke, Kjerstin H W, Strating, Jeroen R P M, Pürstinger, Gerhard, de Vries, Erik, de Haan, Cornelis A M, Neyts, Johan, van Kuppeveld, Frank J M

Journal:

Year:

2012

Language:

english

File:

PDF, 1.38 MB

english, 2012

3

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

Nai-Yun Hsu, Olha Ilnytska, Georgiy Belov, Marianita Santiana, Ying-Han Chen, Peter M. Takvorian, Cyrilla Pau, Hilde van der Schaar, Neerja Kaushik-Basu, Tamas Balla, Craig E. Cameron, Ellie Ehrenfeld

Journal:

Year:

2010

Language:

english

File:

PDF, 1.98 MB

english, 2010

4

Role of antibodies in controlling dengue virus infection

Hilde M. van der Schaar, Jan C. Wilschut, Jolanda M. Smit

Journal:

Year:

2009

Language:

english

File:

PDF, 418 KB

english, 2009

5

Cholesterol: fa(s)t-food for enterovirus genome replication

Strating, Jeroen R.P., van der Schaar, Hilde M., van Kuppeveld, Frank J.M.

Journal:

Trends in Microbiology

Year:

2013

Language:

english

File:

PDF, 348 KB

english, 2013

6

Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein

Strating, Jeroen R.P.M., van der Linden, Lonneke, Albulescu, Lucian, Bigay, Joëlle, Arita, Minetaro, Delang, Leen, Leyssen, Pieter, van der Schaar, Hilde M., Lanke, Kjerstin H.W., Thibaut, Hendrik Jan

Journal:

Year:

2015

Language:

english

File:

PDF, 4.69 MB

english, 2015

7

GBF1- and ACBD3-Independent Recruitment of PI4KIIIβ to Replication Sites by Rhinovirus 3A Proteins

Dorobantu, Cristina M., Ford-Siltz, Lauren A., Sittig, Simone P., Lanke, Kjerstin H. W., Belov, George A., van Kuppeveld, Frank J. M., van der Schaar, Hilde M., Lyles, D. S.

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

8

Targeting of the Hydrophobic Metabolome by Pathogens

Helms, J. Bernd, Kaloyanova, Dora V., Strating, Jeroen R. P., van Hellemond, Jaap J., van der Schaar, Hilde M., Tielens, Aloysius G. M., van Kuppeveld, Frank J. M., Brouwers, Jos F.

Journal:

Year:

2015

Language:

english

File:

PDF, 8.31 MB

english, 2015

9

Dissecting the Cell Entry Pathway of Dengue Virus by Single-Particle Tracking in Living Cells

van der Schaar, Hilde M., Rust, Michael J., Chen, Chen, van der Ende-Metselaar, Heidi, Wilschut, Jan, Zhuang, Xiaowei, Smit, Jolanda M., Farzan, Michael

Journal:

Year:

2008

Language:

english

File:

PDF, 729 KB

english, 2008

10

Immature Dengue Virus: A Veiled Pathogen?

Rodenhuis-Zybert, Izabela A., van der Schaar, Hilde M., da Silva Voorham, Júlia M., van der Ende-Metselaar, Heidi, Lei, Huan-Yao, Wilschut, Jan, Smit, Jolanda M., Gale, Michael

Journal:

Year:

2010

Language:

english

File:

PDF, 385 KB

english, 2010

11

Fat(al) attraction: Picornaviruses Usurp Lipid Transfer at Membrane Contact Sites to Create Replication Organelles

van der Schaar, Hilde M., Dorobantu, Cristina M., Albulescu, Lucian, Strating, Jeroen R.P.M., van Kuppeveld, Frank J.M.

Journal:

Trends in Microbiology

Year:

2016

Language:

english

File:

PDF, 1.90 MB

english, 2016

12

Mutations in Encephalomyocarditis Virus 3A Protein Uncouple the Dependency of Genome Replication on Host Factors Phosphatidylinositol 4-Kinase IIIα and Oxysterol-Binding Protein

Dorobantu, Cristina M., Albulescu, Lucian, Lyoo, Heyrhyoung, van Kampen, Mirjam, De Francesco, Raffaele, Lohmann, Volker, Harak, Christian, van der Schaar, Hilde M., Strating, Jeroen R. P. M., Gorbale

Journal:

Year:

2016

Language:

english

File:

PDF, 2.34 MB

english, 2016

13

Tyrphostin AG1478 inhibits encephalomyocarditis virus and hepatitis C virus by targeting phosphatidylinositol 4-kinase IIIα

Dorobantu, Cristina M., Harak, Christian, Klein, Rahel, van der Linden, Lonneke, Strating, Jeroen R.P.M, van der Schaar, Hilde M., Lohmann, Volker, van Kuppeveld, Frank J.M.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 1.52 MB

english, 2016

14

How antibodies alter the cell entry pathway of dengue virus particles in macrophages

Ayala-Nunez, Nilda V., Hoornweg, Tabitha E., van de Pol, Denise P.I., Sjollema, Klaas A., Flipse, Jacky, van der Schaar, Hilde M., Smit, Jolanda M.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.23 MB

english, 2016

15

Uncovering oxysterol-binding protein (OSBP) as a target of the anti-enteroviral compound TTP-8307

Albulescu, Lucian, Bigay, Joëlle, Biswas, Bishyajit, Weber-Boyvat, Marion, Dorobantu, Cristina M., Delang, Leen, van der Schaar, Hilde M., Jung, Young-Sik, Neyts, Johan, Olkkonen, Vesa M., van Kuppeve

Journal:

Antiviral Research

Year:

2017

Language:

english

File:

PDF, 1.86 MB

english, 2017

16

Direct-acting antivirals and host-targeting strategies to combat enterovirus infections

Bauer, Lisa, Lyoo, Heyrhyoung, van der Schaar, Hilde M, Strating, Jeroen RPM, van Kuppeveld, Frank JM

Journal:

Current Opinion in Virology

Year:

2017

Language:

english

File:

PDF, 968 KB

english, 2017

17

Escaping Host Factor PI4KB Inhibition: Enterovirus Genomic RNA Replication in the Absence of Replication Organelles

Melia, Charlotte E., van der Schaar, Hilde M., Lyoo, Heyrhyoung, Limpens, Ronald W.A.L., Feng, Qian, Wahedi, Maryam, Overheul, Gijs J., van Rij, Ronald P., Snijder, Eric J., Koster, Abraham J., Bárcen

Journal:

Year:

2017

Language:

english

File:

PDF, 5.20 MB

english, 2017

18

Modulation of proteolytic polyprotein processing by coxsackievirus mutants resistant to inhibitors targeting phosphatidylinositol-4-kinase IIIβ or oxysterol binding protein

Lyoo, Heyrhyoung, Dorobantu, Cristina M., van der Schaar, Hilde M., van Kuppeveld, Frank J.M.

Journal:

Antiviral Research

Year:

2017

Language:

english

File:

PDF, 1.08 MB

english, 2017

19

ACBD3 Is an Essential Pan-enterovirus Host Factor That Mediates the Interaction between Viral 3A Protein and Cellular Protein PI4KB

Lyoo, Heyrhyoung, van der Schaar, Hilde M., Dorobantu, Cristina M., Rabouw, Huib H., Strating, Jeroen R. P. M., van Kuppeveld, Frank J. M., Racaniello, Vincent R.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.45 MB

english, 2019

20

Origins of Enterovirus Replication Organelles Established by Whole-Cell Electron Microscopy

Melia, Charlotte E., Peddie, Christopher J., de Jong, Anja W. M., Snijder, Eric J., Collinson, Lucy M., Koster, Abraham J., van der Schaar, Hilde M., van Kuppeveld, Frank J. M., Bárcena, Montserrat, B

Journal:

Year:

2019

Language:

english

File:

PDF, 3.01 MB

english, 2019

21

Origins of Enterovirus Replication Organelles Established by Whole-Cell Electron Microscopy

Melia, Charlotte E., Peddie, Christopher J., de Jong, Anja W. M., Snijder, Eric J., Collinson, Lucy M., Koster, Abraham J., van der Schaar, Hilde M., van Kuppeveld, Frank J. M., Bárcena, Montserrat, B

Journal:

Year:

2019

File:

PDF, 3.01 MB

2019